Skip to main content
Mental Health

Substance Use Disorder Treatment: Medication Costs in Canada

Medications for opioid, alcohol, and tobacco use disorders are effective and increasingly covered. Here is what they cost and how to access them in Canada.

TransparentMedz Team
March 22, 2026
4 min read
749 words

Medication-Assisted Treatment: Breaking Down Costs

Substance use disorders affect over 6 million Canadians in some form, and medication-assisted treatment (MAT) is one of the most effective approaches. Yet many people do not access treatment because they are unsure about costs or coverage. The reality is that most substance use medications are affordable and increasingly covered by provincial health plans.

Opioid Use Disorder (OUD)

Opioid Agonist Therapy (OAT)

MedicationFormMonthly CostProvincial Coverage
MethadoneLiquid (daily dosing)$100–$200 (pharmacy cost)Covered in all provinces
Buprenorphine/naloxone (Suboxone)Sublingual tablet/film$250–$450 (brand)Covered in all provinces
Buprenorphine/naloxone (generic)Sublingual tablet$100–$200Covered in all provinces
Slow-release oral morphine (Kadian)Capsule$150–$300Covered (most provinces, Special Auth.)
Injectable hydromorphone (iOAT)Injection (clinic-based)Clinic-providedCovered (select programs)
Key point: In every Canadian province, OAT is covered by the provincial drug plan regardless of income or insurance status. This includes the cost of the medication and, in many cases, the dispensing fee.

Naltrexone for OUD

FormBrandMonthly CostCoverage
Oral naltrexoneReVia$50–$90 (generic $25–$50)Covered (most provinces)
Injectable naltrexoneVivitrol$1,200–$1,500Not available in Canada

Alcohol Use Disorder (AUD)

MedicationBrandGeneric Cost/MonthEvidenceCoverage
Naltrexone (oral)ReVia$25–$50StrongCovered (most provinces)
AcamprosateCampral$40–$70ModerateCovered (some provinces)
DisulfiramAntabuse$20–$40ModerateCovered (most provinces)
Topiramate (off-label)Topamax$15–$30 genericModerateCovered (for epilepsy indication)
Gabapentin (off-label)Neurontin$10–$25 genericEmergingCovered
Naltrexone is the most cost-effective option for alcohol use disorder at $25–$50/month with strong evidence for reducing heavy drinking days.

Tobacco/Nicotine Use Disorder

TreatmentBrandMonthly CostCoverage
VareniclineChampix$80–$130Covered (most provinces)
BupropionZyban$60–$90 (generic $15–$30)Covered (most provinces)
Nicotine patch (21mg)Nicoderm$80–$120Some provinces
Nicotine gumNicorette$50–$90Rarely covered
Nicotine patch (generic)Store brand$40–$70Rarely covered
Varenicline (Champix) has the highest quit rates and is covered by most provincial drug plans. Check with your province, as several offer free smoking cessation programs that include medications.

Provincial Smoking Cessation Programs

ProvinceFree Medications?Program
OntarioYes (varenicline, NRT)STOP Program
British ColumbiaYes (varenicline, NRT)QuitNow
AlbertaYes (limited supply)AlbertaQuits
QuebecPartial (co-insurance)RAMQ
Nova ScotiaYesTobacco-Free Nova Scotia

Cannabis Use Disorder

There are currently no approved medications specifically for cannabis use disorder. Off-label treatments being studied include:

  • N-acetylcysteine (NAC): $15–$25/month OTC — some evidence in adolescents
  • Gabapentin: $10–$25/month — early evidence for withdrawal symptoms

Accessing Treatment

Step 1: Talk to Your Doctor

Any physician can prescribe naltrexone, acamprosate, or smoking cessation medications. For opioid agonist therapy, physicians need an exemption under the Controlled Drugs and Substances Act (or equivalent provincial authorization), though this requirement has been simplified in recent years.

Step 2: Confirm Provincial Coverage

Call your provincial drug plan or check their formulary online. All OAT medications are covered. For alcohol and tobacco medications, coverage varies.

Step 3: Compare Pharmacy Prices

Use TransparentMedz to compare costs, especially for medications with co-pays. The difference between pharmacies can be $10–$30/month for medications like Suboxone.

Step 4: Check Specialized Programs

  • Canadian Mental Health Association: Connects individuals to local treatment resources
  • Connex Ontario / provincial equivalents: Free helplines for substance use treatment referrals
  • Health Canada Special Access Program: For medications not yet approved in Canada

The Bottom Line

Medication-assisted treatment for substance use disorders is effective, affordable, and increasingly covered across Canada. Opioid agonist therapy is free in every province, alcohol medications cost $25–$70/month generic, and smoking cessation programs offer free medications in many provinces. Use TransparentMedz to find the lowest pharmacy prices and remove cost as a barrier to recovery.

Share this article

Ready to save on your prescriptions?

Compare prices across Canadian pharmacies and find the lowest cost for your medication.

Compare Prices Now